Cures from live cultured corals
CORAL BIOME cultivates corals and studies their biological and chemical diversity to discover and develop marine natural products of interest for human health.
From corals to anti-cancer drugs
The marine world is an under-explored and threatened reservoir of biochemical diversity for drug discovery.
Bioactive compounds derived from corals have great potential in addressing major health concerns such as cancer, infections, and inflammatory diseases.
Coral culture & sourcing for drug discovery
By cultivating corals in order to explore their pharmaceutical potential, we are simultaneously protecting them. All of the corals that we use for drug discovery are aquacultured, which helps decrease the collection pressure on their wild populations. Corals are genetically analyzed and carefully selected for their biological and chemical properties, and then grown in our, or in one of our international partners’ laboratories worldwide. This marine biomass production is also available for sale to biotech and pharma companies.
Innovative ecotargeting strategy
Our deep understanding of the biology, behavior, and ecology of coral species allows us to accurately target the most promising species to investigate their chemical properties. Furthermore, our aquacultural expertise maximizes growth rates to guarantee a consistent supply of rare compounds. This innovative and sustainable ecotargeting strategy increases the likelihood of discovering potent drugs and already allowed us to identify 30 bioactive compounds of interest against cancer, along with infectious and inflammatory diseases. We also offer ecotargeting consulting to companies willing to accelerate and reduce the costs of their bio-prospection.
Curing cancer with corals
Among marine natural products discovered in corals (mostly octocorals), 41% are cytotoxic molecules with potent anti-cancer activity. Among them, we revisited the cytotoxic effect of a powerful toxin called palytoxin and its potential for cancer treatment (proprietary patent). CORAL BIOME discovered a potent coral strain and developed a patented extraction process that affords us the production of large quantities of pure palytoxin. Subsequent testing showed that it can be used as an efficient drug against multidrug resistant cancers at very low concentrations (picomolar range). Pre-clinical trials starting soon!